For those Christians who believe their Bible is the word of God, the literal truth, one man is held up as the antichrist, he is Charles Darwin, their reasoning?, for leading millions of Christians astray with a very different account of creation, evolution by natural selection. In this new HBO film we get a look into this fast-growing branch of Christians in America, who have a very hardline, literal and creationist view of the Bible.

Through a selection of interview with Darwin historians, biographers, ministers and creationist Christians, along with letters and writings of Darwin, this documentary attempts to take a balanced look at this 150-year old debate. Creation vs. Evolution.